Local hero Burn handed Newcastle a well-deserved lead just before halftime, heading home a corner in the 45th minute.
Fueled by overwhelming support from their passionate black-and-white-clad fans, Newcastle took complete control of the match seven minutes into the second half. Swedish striker Isak coolly slotted a shot past Liverpool goalkeeper Caoimhín Kelleher to extend their advantage.
Liverpool, who lead the Premier League, managed a late response through Federico Chiesa’s goal in stoppage time, but it was too late, as Eddie Howe’s side held firm to secure the club’s first domestic trophy since 1955.
After losing to Manchester United in the Carabao Cup final two years ago, Newcastle arrived with renewed focus and determination on Sunday, channeling the energy from their supporters as they sought to make history.
Liverpool, meanwhile, appeared lackluster, struggling with the aftermath of their midweek Champions League exit following a penalty shootout loss to Paris Saint-Germain.
The game started cautiously, but it was Newcastle who looked more dangerous. Although they had little to show for their early pressure, a Sandro Tonali shot narrowly missing the target indicated their growing intent.
Liverpool seemed content to reach halftime level until Burn broke the deadlock right before the break. The defender, who had earned his first England call-up earlier in the week, sent Newcastle fans into delirium in the 45th minute.
Burn, towering over Liverpool’s smaller Alexis Mac Allister, powered home a header from Kieran Trippier’s corner, sending the ball into the far post beyond a diving Kelleher.
It was Burn’s first goal of the season and Newcastle’s first at Wembley in 25 years, since Rob Lee’s strike in a losing FA Cup semifinal against Chelsea.
Newcastle didn’t have to wait long for a second. Just seven minutes after the restart, Isak, whose earlier goal was ruled out for offside, latched onto a header from Jacob Murphy. The Swedish forward made no mistake, firing past Kelleher with precision, much to the delight of the black-and-white crowd.
Liverpool’s first shot on target came from substitute Curtis Jones, whose fierce drive forced a save from Nick Pope. But the situation could have been worse for the Reds, as Isak was denied a close-range goal by Kelleher shortly after.
Despite the lengthy wait for silverware, Newcastle’s path to victory wasn’t without a touch of drama. Chiesa’s well-executed finish in stoppage time, initially ruled offside but later allowed, caused nervous moments for the Magpies before the final whistle confirmed their triumph, finally ending decades of frustration.